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EmOftal

30 film-coated tablets of 700 mg

 

For the treatment of bleeding and capillary protection in Ophthalmology

 

 

  • Improvement of capillary tone and permeability

  • Promotes the removal of exudate from interstitial spaces thanks to its draining activity

  • It inhibits the release of proinflammatory cytokines

 

 

MECHANISMS OF ACTION OF THE INDIVIDUAL COMPONENTS


A-LIPOIC ACID


Direct antioxidant activity on the whole radical spectrum.

 

Indirect antioxidant activity (increases the synthesis of REDUCED GLUTATÍONE).

 

In diabetes, high concentrations of AGES ( AGEs, from the English "Advanced Glycation End-products" are compounds derived from sugar created in the body. Smoking or eating certain foods cooked at high temperatures increases the deposits of AGE in the arteries and this can lead to insulin resistance or other health problems ) could play a key role in the apoptosis of retinal capillaries and oxidative stress is involved in this process.

The reduction of AGES in the retinal capillaries could prevent their apoptosis and, ultimately, the development of diabetic retinopathy.
Administration of a-lipoic acid reduces the acute mitochondrial oxidative effect induced by ACROLEIN on the retinal pigment epithelium and therefore may reduce or prevent its degeneration induced by a variety of oxidative sources.

(AGES = precursors of free radicals at the vascular level), (ACROLEIN = main oxidative compound present in cigarette smoke).

 

CENTELLA


Centella on fibroblasts acts by turning the protein synthesis from collagen to glycosaminoglycans, thus favoring the proper functioning of the micro - vascular - tissue unit and stimulating the fibroblastic synthesis of fibronectin with consequent increase
the consistency of the vessel wall.

The combination of Centella and Sweet Clover has been shown to improve retinal sensitivity in the long term in Type 2 Diabetes Patients with Cystoid Macular Edema.
The multiplicity of Centella's activities is associated with six important mechanisms, all interconnected and modulators of each:

  1. control of capillary filtration and edema;

  2. strong antioxidant power effective on oxidative stress associated with inflammation or infection and synergistic action with other oxidants;

  3. anti-inflammatory activity;

  4. modulation of local growth factors;

  5. modulation of angiogenesis;

  6. modulation of collagen production which avoids a too slow or too rapid healing process.

Furthermore, Centella, even at low doses, would be useful in promoting the healing of corneal lesions

ORTHOSIPHON


Orthosiphon exhibits dose-dependent diuretic activity.
Orthosiphon demonstrates important antioxidant activities and could be considered an immunomodulatory agent.
Sinensetin, a constituent flavonoid of Orthosiphon, possesses significant anti-inflammatory properties so much that it can be considered for the development of new anti-inflammatory therapies.

MELILOT


The combination of Centella and Sweet Clover has been shown to improve retinal sensitivity in the long term in Type 2 Diabetes Patients with Cystoid Macular Edema.
Anti-edema effect.

RUSCO


Anti-inflammatory and vasoconstrictor activity; in this way a narrowing action of the vessels is obtained which involves the reduction of the leakage of liquids.


BLUEBERRY


Its anthocyanosides improve the elasticity of the vessels, have an anti-haemorrhagic action and protect against damage from free radicals, reduce capillary permeability and prevent micro hemorrhages, which are particularly dangerous at the level of retinal blood flow.
Another important function of these molecules is to intervene on the mechanisms of vision: they are able to increase the speed of regeneration of the retinal purpura, with an effect of improving vision, especially at night.

VITAMIN E


A recent study has shown that Vitamin E reduces plasma levels of reactive oxygen species (ROS) and central macular thickness in diabetic patients with proliferative retinopathy.

 

Indicated:

 

In the prevention of cystoid macular edema and in edema control after retinal detachment surgery.

Emovitreo

Hypoema from uveitis

Saottoconjunctival hemorrhage

post-operative bruises such as, for example, from blepharoplasty.

 

THE 4 ACTIONS OF EMOFTAL

 

  1. SYNERGIC ACTION : of Centelle, Blueberry, Sweet Clover, Rusco for the recovery of capillary tone and veins with physiological restoration of the permeability of the microcirculation

  2. DRAINING and ANTIEDEMIGENE ACTION of Sweet Clover and Orthosiphon on extracapillary exudate

  3. ANTI-INFLAMMATORY, ANTI-RADICAL and ANTIBATTERC ACTION of Orthosiphon

  4. SYNERGIC ANTIOXIDANT ACTION of Alpha Lipoic Acid, Vitamin E and Orthosiphon to contrast oxidative stress supported by the wide spectrum of free radicals (superoxide anion and AGE) released as a result of hyperglycemia.

 

Recommended daily dose and method of use:

 

Subconjunctival and vitreous hemorrhages:

1 cps x 2 x 15 days

Cystoid macular edema prevention:

1 cps three days before cataract surgery and for 60 days after

Advanced non-proliferative diabetic retinopathy:

2 cps x 2 x 5 days - then 1 cps x 3 x 15 days - then 1 cps die x 45 days

Mild and moderate diabetic retinopathy np; stage III and IV hypertensive retinopathy:

1 cps x 2 for 20 days - then 1 cps x 1 x 60 days

I and II stage hypertensive retinopathy; atherosclerotic retinopathy:

1 capsule per day x 60 days

 

Warnings:

 

Keep out of reach of children. Food supplements are not intended as a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Do not consume after the expiry date of conservation.

The last term of conservation refers to the product in an intact and correctly stored package. For the duration of the supplement, follow the advice of the nutritionist.

 

Additional warnings:

 

for the use of the product it is advisable to consult the doctor's opinion. In rare cases, lipoic acid can cause hypoglycemia.

 

Precautions:

 

If you are taking antiplatelet or anticoagulants, consult your doctor before taking the product.

 

 

30 film-coated tablets of 700 mg

Net weight 21 g

 

Eye OphthalResearch Srl

 

Bibliography

EmOftal
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